Alphabetical List Of Sleep Medications Average ratng: 4,2/5 4953 reviews

Other names: Difficulty sleeping; Dyssomnia; Inability to sleep; Sleeplessness; Wakefulness

  • Medication List

About Insomnia: Inability to sleep, abnormal wakefulness.

See also: sub-topics

Drugs Used for Insomnia

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA AlcoholReviewsRatingPopularity
estazolamRx X 4 X 18 reviews

Generic name: estazolam systemic

Brand name: Prosom

Drug class: benzodiazepines

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

doxylamineRx/OTC B N X 140 reviews
6.0

Generic name: doxylamine systemic

Brand names: Unisom SleepTabs, Sleep Aid, Care One Sleep Aid, Equaline Sleep Aid, Equate Sleep Aid, Nighttime Sleepaid…show all

Drug class: miscellaneous anxiolytics, sedatives and hypnotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

triazolamRx X 4 X 46 reviews
8.0

Generic name: triazolam systemic

Brand name: Halcion

Drug class: benzodiazepines

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Unisom SleepTabsRx/OTC B N X 47 reviews
6.0

Generic name: doxylamine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics

For consumers: dosage, interactions, side effects

Tylenol PMRx/OTC N N X 14 reviews
6.0

Generic name: acetaminophen / diphenhydramine systemic

Drug class: analgesic combinations

For consumers: dosage, interactions, side effects

olanzapineOff LabelRx C N X 42 reviews
7.0

Generic name: olanzapine systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

secobarbitalRx D 2 X 10 reviews
10

Generic name: secobarbital systemic

Brand names: Seconal, Seconal Sodium

Drug class: barbiturates

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts

SeconalRx D 2 X 5 reviews
10

Generic name: secobarbital systemic

Drug class: barbiturates

For consumers: dosage, interactions, side effects

zaleplonRx C 4 X 97 reviews
5.0

Generic name: zaleplon systemic

Brand name: Sonata

Drug class: miscellaneous anxiolytics, sedatives and hypnotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

suvorexantRx C 4 X 424 reviews
3.0

Generic name: suvorexant systemic

Brand name: Belsomra

Drug class: miscellaneous anxiolytics, sedatives and hypnotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

diphenhydramine / ibuprofenOTC N N X 2 reviews
7.0

Generic name: diphenhydramine / ibuprofen systemic

Brand names: Advil PM, Ibuprofen PM, Motrin PM

Drug class: analgesic combinations

For consumers: dosage, interactions,

For professionals: Prescribing Information

quazepamRx C 4 X 5 reviews
9.0

Generic name: quazepam systemic

Brand name: Doral

Drug class: benzodiazepines

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, Prescribing Information

ramelteonRx C N X 90 reviews
4.0

Generic name: ramelteon systemic

Brand name: Rozerem

Drug class: miscellaneous anxiolytics, sedatives and hypnotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Seconal SodiumRx D 2 X 5 reviews
10

Generic name: secobarbital systemic

Drug class: barbiturates

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

EdluarRx C 4 X 11 reviews
8.0

Generic name: zolpidem systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

acetaminophen / diphenhydramineRx/OTC N N X 19 reviews
6.0

Generic name: acetaminophen / diphenhydramine systemic

Brand names: Tylenol PM, Aceta-Gesic, Excedrin PM, Headache Relief PM, Legatrin PM, Mapap PM, Midol PM, Night Time Pain, Pain Relief PM Extra Strength, Percogesic Extra Strength, Tylenol Sore Throat Nighttime, Unisom PM Pain…show all

Drug class: analgesic combinations

For consumers: dosage, interactions,

chloral hydrateRx C 4 X 16 reviews
7.0

Generic name: chloral hydrate systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics

For consumers: dosage, interactions,

Compoz Nighttime Sleep AidRx/OTC B N X 2 reviews
9.0

Generic name: diphenhydramine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

DoralRx C 4 X 3 reviews
9.0

Generic name: quazepam systemic

Drug class: benzodiazepines

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

NytolRx/OTC B N X 13 reviews
4.0

Generic name: diphenhydramine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

oxazepamOff LabelRx N 4 X 8 reviews
7.0

Generic name: oxazepam systemic

Drug class: benzodiazepines

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

pentobarbitalOff LabelRx D M X 1 review
10

Generic name: pentobarbital systemic

Drug class: barbiturates

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Simply SleepRx/OTC B N X 14 reviews
5.0

Generic name: diphenhydramine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

SominexRx/OTC B N X 34 reviews
6.0

Generic name: diphenhydramine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

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tasimelteonRx C N X 1 review
10

Generic name: tasimelteon systemic

Brand name: Hetlioz

Drug class: miscellaneous anxiolytics, sedatives and hypnotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Topics under Insomnia

  • Insomnia, Stimulant-Associated(1 drug)
  • Night Terrors(5 drugs)
  • Nightmares(2 drugs)

Alternative treatments for Insomnia

The following products are considered to be alternative treatments or natural remedies for Insomnia. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Insomnia.

Learn more about Insomnia

IBM Watson Micromedex

Symptoms and treatments

Drugs.com Health Center

Mayo Clinic Reference

Legend

RxPrescription Only
OTCOver the Counter
Rx/OTCPrescription or Over the Counter
Off LabelThis medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
AAdequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
BAnimal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
CAnimal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
DThere is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
XStudies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
NFDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
NIs not subject to the Controlled Substances Act.
1Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
XInteracts with Alcohol.

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Further information

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